Dr. Ian James Martins
Address:
School of Medical and Health Sciences, Edith Cowan University, Joondalup Campus, Perth, WA, Australia
Academic Metrics:
- h-index: 39
- i-10 index: 109
- Total Citations:5559
Research Interests:
- Metabolism and Endocrinology
- Aging and Neurodegeneration
- Diabetes and Obesity Research
- Mitochondrial Dysfunction
- Nutritional Interventions in Chronic Diseases
- Biomarkers for Disease Progression
- Preventive Health Strategies
Biography:
Dr. Ian James Martins is a prolific researcher whose work investigates the critical links between metabolic disorders and neurodegenerative diseases. His primary focus is on the pathogenesis of Alzheimer's disease, which he argues is closely connected to insulin resistance, dyslipidemia, and mitochondrial dysfunction—hallmarks of conditions like diabetes and obesity. Dr. Martins has proposed and extensively studied the concept of a "lipotoxicity-induced cascade" that impairs amyloid-beta clearance from the brain, leading to neurodegeneration. A central theme in his research is the promotion of non-pharmacological interventions, such as specific diets, nutraceuticals, and lifestyle modifications, to prevent or delay the onset of age-related diseases. His contributions have significantly advanced the understanding of Alzheimer's as a metabolic disease.
Education Details:
- PhD in Medical Science, University of Western Australia, Australia
- MSc in Biochemistry, University of Western Australia, Australia
- BSc (Hons), University of London, UK
Professional Background:
- Honorary Senior Fellow, School of Medical and Health Sciences, Edith Cowan University (ECU), Western Australia (Present)
- Formerly served as a researcher and fellow at various institutions focusing on metabolism, aging, and neurobiology.
Achievements:
- Recognized as a leading authority on the metabolic theory of Alzheimer's disease.
- Authored a vast number of highly cited articles and reviews in prominent international journals.
- Editor and reviewer for numerous journals in the fields of aging, nutrition, and neuroscience.
Current Research Projects
His current research continues to explore the molecular pathways connecting accelerated aging with chronic diseases. He is investigating how nutritional interventions can reverse cellular senescence and improve brain glucose metabolism to mitigate neurodegeneration. His work also focuses on the role of specific genes (e.g., Sirtuin 1, Klotho) as therapeutic targets for age-related metabolic and neurological disorders.
Academic Profiles of Dr. Ian James Martins
Publications:
Dr. Martins maintains an exceptionally high publication output, with his recent work continuing to build upon the connections between lifestyle, nutrition, and the prevention of chronic age-related diseases.
List of 5 Recent Publications:
- Martins, I. J. (2025). Anti-Aging Gene Research Has Now Become Essential to Prevent Global Chronic Diseases. Acta Scientific Neurology, 8(1), 1-2.
- Martins, I. J. (2024). Global Food Intake Has Now Become the Major Cause of Senescence and Chronic Diseases. Journal of Clinical Nutrition and Dietetics, 10(3), 1-3.
- Martins, I. J. (2024). Anti-Aging Gene Regulation is Now the Global Target to Prevent Insulin Resistance and Neurodegeneration. Journal of Gerontology and Geriatric Medicine, 10, 1-3.
- Martins, I. J. (2024). Anti-Aging Genes and Diets are Now Connected to the Prevention of Insulin Resistance and Alzheimer’s Disease. EC Neurology, 16(5), 1-4.
- Martins, I. J. (2024). Sirtuin 1, the Anti-Aging Gene Should Now Be the Global Target to Prevent Chronic Diseases. Journal of Pathology and Disease Biology, 9(2), 1-3.
Last Updated on October 12, 2025